Figure 2.

Sequence similarities (%) between six human nuclear steroid hormone receptors and their corresponding orthologues in 13 species. Sequence similarities of the full sequences are presented on the left and similarities of the ligand binding domains are presented on the right. AR, androgen receptor; PGR, progesterone receptor; ESR1, oestrogen receptor 1 (α); ESR2, oestrogen receptor 2 (β); NR3C1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); NR3C2, nuclear receptor subfamily 3, group C, member 2 (mineralocorticoid receptor). Percentage similarities are emphasized using a coloured heat map. Empty cells indicate that evidence for an orthologue is lacking in current genome versions and gene builds. Asterisk denotes missing value owing to errors in current gene build. (Online version in colour.)