Figure 1.

Connections between key components of effects-based prioritization strategy for human and veterinary pharmaceuticals. Rectangular shapes describe the components considered for prioritization. Long dashed line represents instances where data or information derived from one of the components can be used to better understand or guide decisions within another component. Small dashed line represents parameters assessed within component (a). Solid arrows represent the information used to guide prioritization derived from each component. AOPs, adverse outcome pathways. (a–c) Correspond to §2a,b and c in the text.