Fig. 5.

The effect of Rg3-enriched Korean Red Ginseng (REKRG) on aortic structure. (A) REKRG treatment increased nitric oxide (NO) production. Metabolites of NO (nitrite and nitrate) were measured in the serum. *p < 0.05 compared with control. Data represent the mean ± standard deviation (SD; n = 4–5). (B,C) The intima-media thickness and cross sectional area were quantified using a computer-assisted imaging device. The mean value of the vessel wall thickness from the endothelial surface to the adventitia was determined from five different locations spanning the entire cross-section. *p < 0.05 compared with Wistar-Kyoto rats. **p < 0.05 compared with SHR. Data represent the mean ± SD (n = 5–6). (D) Representative images of hematoxylin and eosin-stained aortic rings.