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. 2014 Oct 30;4:6841. doi: 10.1038/srep06841

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(a) Genomic structures of human MUSK and mouse Musk genes. Constitutive and alternative exons are shown in green and red boxes, respectively. Black boxes indicate untranslated regions (UTRs) and thin lines indicate introns. Alternative skipping of exons annotated in ENSEMBL 76 are shown by blue connecting lines. (b) Domain structure of MuSK. Fz-CRD is a Wnt-responsive domain encoded by exon 10 coding for 6 cysteines (light blue-colored region of Fz-CRD) and exon 11 coding for 4 cysteines (yellow-colored region of Fz-CRD) in human. SS, signal sequence; TM, transmembrane domain.