Table 1.
Demographics, comorbidities, severity on admission, clinical course, microbiological isolations, and outcome.
| Patient 1 | Patient 2 | Patient 3 | |
|---|---|---|---|
| Age | 51 | 43 | 24 |
| Gender | Male | Female | Male |
| BMI | 27 | 32 | 24 |
| Immunosuppression | No | No | No |
| Comorbidities | Gout | Hypothyroidism, depression, chronic headache | None |
| SOFA score on admission | 6 | 4 | 6 |
| CURB-65 score on admission | 0 | 1 | 2 |
| Hospital day when MV was started | 3rd | 2nd | 2nd |
| Hospital day when ECMO was started | 7th | 2nd | 4th |
| Length of ECMO (days) | 20 | 26 | 15 |
| Hospital day when influenza virus assay was performed and oseltamivir started | 3rd | 2nd | 1st |
| Length of oseltamivir therapy (days) | 13 | 9 | 30 |
| Nosocomial pathogens isolated | C. parapsilosis on throat specimen and S. epidermidis on BAS | P. aeruginosa MDR, C. albicans, C. glabrata, and C. parapsilosis on BAS | P. aeruginosa MDR, Flavobacterium, and C. indologenes on BAS |
| LP and SP urinary antigens | Negative | Negative | Negative |
| CP, MP, and LP IgM and IgG | Negative | Negative | Negative |
| Outcome | Alive | Alive | Alive |
MV: mechanical ventilation; ECMO: extracorporeal membrane oxygenation; LP: L. pneumophila; SP: S. pneumoniae; CP: C. pneumoniae; MP: M. pneumoniae; BAS: bronchial aspirate; MDR: multidrug resistant (used for pathogens resistant to at least three drugs from different antibiotic categories).