Table 2.
Occupancy* |
Mean Abundance | ||||||
---|---|---|---|---|---|---|---|
Species | BE | PBB | CF | (%) | Mean Contribution | % Contribution | Cumulative % |
Haemophilus influenzae | 12 | 11 | 19 | 23.22 | 18.79 | 37.44 | 37.44 |
Streptococcus mitis | 18 | 12 | 25 | 14.59 | 8.45 | 16.84 | 54.28 |
Prevotella melaninogenica | 16 | 11 | 24 | 9.16 | 4.59 | 9.15 | 63.43 |
Veillonella dispar | 19 | 12 | 24 | 4.48 | 3.90 | 7.77 | 71.20 |
Fusobacterium nucleatum | 17 | 11 | 21 | 2.63 | 1.99 | 3.97 | 75.17 |
Neisseria flavescens | 12 | 11 | 19 | 5.04 | 1.73 | 3.44 | 78.61 |
Porphyromonas catoniae | 17 | 11 | 18 | 1.66 | 1.05 | 2.09 | 80.70 |
Haemophilus parainfluenzae | 15 | 10 | 16 | 1.30 | 1.04 | 2.06 | 82.76 |
Porphyromonas gingivalis | 17 | 9 | 17 | 1.60 | 0.97 | 1.92 | 84.69 |
Prevotella nanceiensis | 13 | 11 | 15 | 0.85 | 0.54 | 1.08 | 85.77 |
Prevotella histicola | 12 | 7 | 19 | 0.81 | 0.46 | 0.92 | 86.69 |
Granulicatella adiacens | 15 | 10 | 19 | 0.53 | 0.44 | 0.87 | 87.57 |
Prevotella oris | 10 | 4 | 13 | 1.07 | 0.37 | 0.73 | 88.30 |
Sphingomonas echinoides | 9 | 7 | 3 | 0.73 | 0.36 | 0.71 | 89.02 |
Gemella morbillorum | 13 | 11 | 21 | 0.86 | 0.35 | 0.70 | 89.71 |
Prevotella pallens | 16 | 8 | 13 | 0.63 | 0.32 | 0.63 | 90.35 |
Definition of abbreviations: BE = bronchiectasis; CF = cystic fibrosis; PBB = protracted bacterial bronchitis.
Given is occupancy, or the number of patients for each disease group in which a given species was detected. Next is mean % abundance of sequences for a species across the samples it was observed to occupy. Mean contribution represents the average contribution of a given species to the average similarity between samples (overall mean = 50.2%). Percentage contribution is the mean contribution divided by mean similarity across samples. The list of species is not exhaustive, so cumulative % value does not sum to 100%. Species-level identities of detected taxa are reported here. However, given the length of the ribosomal sequences analyzed, these identities should be considered putative.
Total n for each pediatric disease cohort: BE, 19; PBB, 12; CF, 25.