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. 2014 Sep 1;190(5):560–571. doi: 10.1164/rccm.201401-0188OC

Figure 3.

Figure 3.

Programmed death-1 (PD-1) expression in bronchoalveolar lavage (BAL) from patients with sarcoidosis. (A) Comparison of PD-1 expression on CD4+ T cells in the periphery (peripheral blood mononuclear cells [PBMC], n = 65) and BAL (n = 20) of patients with sarcoidosis. (B) Percent PD-1+ CD4+ cells in peripheral and local environments of 10 patients with sarcoidosis. (C) BAL from disease control subjects (DC, n = 9) and patients with sarcoidosis (S, n = 20). (D) Percent PD-1+ CD4+ memory T-cell subsets in BAL according to sarcoidosis clinical disease activity. BAL, 11 subjects during active disease, 9 subjects with resolved disease, 9 disease control subjects (DC), and 4 healthy control subjects (HC). (E) Percent PD-1+ CD4+, Th17, and T regulatory cells. *P < 0.001; **P < 0.05.