Figure 2.

Carriers of rs315952C have increased LPS-evoked plasma IL1RA levels. At each time point, the median (dot or square) and interquartile range (whiskers) are shown, stratified by rs315952C allele carriage. The y axis is interrupted to allow discrimination at the earlier time points, when the concentration of plasma IL1RA was 100-fold lower. Repeated measures analysis was performed by linear mixed effects model with an individual-specific random effect and with quantile transformation of the data at each time point.