. 2014 Sep;16(3):419–429. doi: 10.31887/DCNS.2014.16.3/aguidotti

Table 1. Epigenetic signature in the prefrontal cortex of psychotic patients. APOBEC, apolipoprotein B mRNA-editing enzyme complex; BNDF, brain-derived neurotrophic factor; DNMT, DNA methyltransferase; GAD, glutamic acid decarboxylase; TET, tet methylcystosine dioxygenase.

Component changes in psychosis
DNMT1, DNMT3A	Increased^{1,10-12,32,33}
TET 1, 2, 3	Increased^26,42
APOBEC 3A, 3C	Decreased²⁶
BDNF, Reelin promoters	Enrichment of 5-mC mark^{1,15,21,37,40}
BDNF, GAD67 promoters	Enrichment of 5-hmC mark^21,26
BDNF, Reelin, GAD67 expression	Downregulation^{2,6,7,9,13,14}