Table 7.
Random forest results males.
| SNP | beta.hat | lr | mChr | mPos | pval | pval.bh | Index gene | Function class |
|---|---|---|---|---|---|---|---|---|
| FULL SAMPLE | ||||||||
| rs10923844 | 6.26 | 13.42 | chr1 | 120000000 | 0.0002 | 0.07 | HSD3B1 | Downstream |
| rs2301267 | 5.66 | 12.38 | chr2 | 48984391 | 0.0004 | 0.07 | LHCGR | Upstream (LHCGR) intronic (STON1-GTF2A1L) |
| rs11897846 | 2.94 | 3.29 | chr2 | 48956512 | 0.07 | 0.66 | LHCGR | Intronic |
| rs10495960 | 3.97 | 3.26 | chr2 | 48960032 | 0.07 | 0.66 | LHCGR | Intronic (LHCGR) missense (GTF2A1L) |
| rs4952922 | 4 | 3.29 | chr2 | 48961396 | 0.07 | 0.66 | LHCGR | Intronic |
| rs988328 | −6.6 | 8.42 | chr6 | 152000000 | 0.004 | 0.35 | ESR1 | Intronic |
| rs4728533 | 1.82 | 0.75 | chr7 | 75586536 | 0.38 | 0.90 | POR | Intronic |
| rs10504255 | 3.63 | 3.64 | chr8 | 59398461 | 0.06 | 0.66 | CYP7A1 | Downstream |
| rs1004467 | 4.04 | 2.85 | chr10 | 105000000 | 0.09 | 0.66 | CYP17A1 | Intronic |
| rs12419334 | 4.62 | 7.34 | chr11 | 71139472 | 0.007 | 0.38 | DHCR7 | Downstream |
| rs12797951 | 4.17 | 6.26 | chr11 | 71143266 | 0.01 | 0.57 | DHCR7 | Downstream |
| rs74091680 | 7.75 | 7.47 | chr12 | 57154822 | 0.006 | 0.38 | HSD17B6 | Intronic |
| rs47340 | 5.66 | 12.8 | chr22 | 43562829 | 0.0003 | 0.07 | TSPO | Downstream (TSPO) 3 prime UTR (TTLL12) |
| rs139036121 | −0.21 | 0.03 | chrX | 8912628 | 0.87 | 0.96 | Xp22 near GWAS hit | Intergenic b/t FAM9A and FAM9B |
| rs5934508 | −0.1 | 0.01 | chrX | 8918776 | 0.92 | 0.97 | Xp22 near GWAS hit | Intergenic b/t FAM9A and FAM9B |
| SUBSET WITH TRANSFERRIN <0.50 ng/dl | ||||||||
| rs56058466 | 9.15 | 6.42 | chr2 | 38328870 | 0.01 | 0.21 | CYP1B1 | Upstream |
| rs4952922 | 11.36 | 17.97 | chr2 | 48961396 | 0.00002 | 0.006 | LHCGR | Intronic |
| rs10495960 | 11.30 | 17.81 | chr2 | 48960032 | 0.00002 | 0.0006 | LHCGR | Intronic (LHCGR) missense (GTF2A1L) |
| rs2301267 | 7.37 | 13.36 | chr2 | 48984391 | 0.0003 | 0.03 | LHCGR | Upstream |
| rs4245818 | 8.94 | 10.78 | chr2 | 48985607 | 0.001 | 0.06 | LHCGR | Upstream (LHCGR) Intronic (STON1-GTF2A1L) |
| rs11682325 | 9.86 | 6.56 | chr2 | 48899807 | 0.01 | 0.21 | LHCGR | Downstream (LHCGR |
| Intronic (STON1-GTF2A1L) | ||||||||
| rs2031367 | 8.74 | 7.83 | chr6 | 87807180 | 0.01 | 0.17 | CGA | Upstream |
| rs6937568 | 12.46 | 5.22 | chr6 | 152153964 | 0.02 | 0.28 | ESR1 | Intronic |
| rs62442039 | 13.38 | 12.90 | chr6 | 152158090 | 0.0003 | 0.03 | ESR1 | Intronic |
| rs10954724 | −4.19 | 3.16 | chr7 | 75597545 | 0.08 | 0.46 | POR | Intronic |
| rs17148944 | 10.69 | 5.96 | chr7 | 75601867 | 0.01 | 0.23 | POR | Intronic |
| rs800667 | 2.91 | 0.41 | chr7 | 99447241 | 0.52 | 0.81 | CYP3A43 | Synonymous |
| rs881671 | −21.87 | 12.79 | chr8 | 59417107 | 0.0003 | 0.03 | CYP7A1 | Upstream |
| rs8190495 | 5.80 | 7.09 | chr9 | 99061884 | 0.01 | 0.18 | HSD17B3 | Intronic |
| rs8190478 | 6.23 | 9.07 | chr9 | 99064883 | 0.003 | 0.12 | HSD17B3 | Upstream |
| rs74091680 | 7.59 | 2.03 | chr12 | 57154822 | 0.15 | 0.55 | HSD17B6 | Intronic |
| rs2277339 | 2.67 | 0.47 | chr12 | 57146069 | 0.49 | 0.82 | HSD17B6 | Upstream (HSD17B6) missense (PRIM1) |
| rs47340 | 6.61 | 6.83 | chr22 | 43562829 | 0.01 | 0.20 | TSPO | Downstream (TSPO) 3 prime UTR (TTLL12) |