Table 1. Current state of NIPT in the United States, Europe, and China.
Region | Company | Service | Diseases tested for | Date started | Number of samples tested | Ref. |
United States | Sequenom | MaterniT21™ PLUS | Trisomy 21/ Trisomy 18/ Trisomy 13/ Turner syndrome/ 22q 11.2 deletion syndrome/ 1p36 deletion syndrome | October 2011 | 100,000 (as of April 16, 2013) | (13) |
Natera | Panorama™ | Trisomy 21/ Trisomy 18/ Trisomy 13/ Turner syndrome/ Triploidy detection / 22q 11.2 deletion syndrome/ 1p36 deletion syndrome | Unknown | Unknown | (14) | |
Verifi | Verifi® | Trisomy 21/ Trisomy 18/ Trisomy 13/ Turner syndrome | March 2012 | Unknown | (15,16) | |
Ariosa | Harmony Prenatal Test™ | Trisomy 21/ Trisomy 18/ Trisomy 13/ Turner syndrome | May 2012 | 40,000 (as of November 13, 2013) | (17) | |
Europe | LifeCodexx | PrenaTest® | Trisomy 21/ Trisomy 18/ Trisomy 13 | August 2012 | Nearly 6,000 (as of August 22,2013) | (18,19) |
China | BGI | NIFTY | Trisomy 21/ Trisomy 18/ Trisomy 13 | May 2010 | 109,582 (as of April 2, 2013) | (12,20) |
Berry genomics | BambniTest | Trisomy 21/ Trisomy 18/ Trisomy 13 | April 2011 | Over 100,000 | (11,21) |
NIPT: noninvasive prenatal testing