Table 2. Age-adjusted time trends in blastomycosis-related mortality rate for sex, race/ethnicity, and geographic region, United States, 1990–2010*.

Variable	Annual percent change† in age-adjusted mortality rates (95% CL)	p value
Sex
F	−2.28 (−3.84, −0.70)	<0.01
M	−2.32 (−3.43, −1.20)	<0.01
Race/ethnicity
White	−1.57 (−2.62, −0.51)	<0.01
Hispanic	‡
Black	−5.12 (−7.19, −3.01)	<0.01
Asian	‡
Native American	‡
Geographic region
Northeast	‡
South	−5.06 (−6.28, −3.28)	<0.01
Midwest	1.70 (0.27, 3.15)	0.02
West	‡
Total	−2.21 (−3.11, −1.29)	<0.01

*CL, confidence limit. 
†Annual percent change based on the Poisson model for death, with year and age group dummy variables as independent variables, and the base population as the offset. No other covariates were adjusted in the model.
‡Few deaths occurred in these categories, and thus, were not included in Poisson regression analyses to avoid inappropriate use of small numbers in Poisson regression modeling.