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. 2014 Sep 26;8(6):2715–2720. doi: 10.3892/ol.2014.2570

Figure 1.

Figure 1

Comparison of circadian gene mRNA expression levels between hepatocellular carcinoma (HCC) tissue (T) and matched peritumoral tissue (N). Box boundaries represent the 25th and 75th percentiles of the observed values; capped bars, the 10th and 90th percentiles; solid line, the median. P-values were calculated by the Wilcoxon test. Per1, Per2, Per3 and Cry2 gene expression levels were higher in the peritumoral tissue than in the HCC tissue. CLOCK, BMAL1, Cry1 and CK1ɛ gene expression levels were similar in the HCC and peritumoral tissue. P<0.05 was considered to indicate a statistically significant difference.