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Plasma levels of sTNFR1 in patients with severe trauma. Traumatic injury upregulated the expression of the soluble receptor, with peak levels 1 day after trauma. Patients in the H-ISS group exhibited the highest sTNFR1 plasma levels at all five time points examined. Data are presented as the means ± SD, n=20 per group. *P<0.01, compared with the healthy controls. sTNFR 1, soluble tumor necrosis factor receptor 1; L/M/H-ISS, low/medium/high injury severity score.
