Histological examination characteristics of pulmonary epithelioid hemangioendothelioma (hematoxylin and eosin staining) (A, case 1; B, case 2; C, case 3; D, case 4). (A) Neoplasms are composed of short cords and nested tumor cells, and interstitial mucus degeneration (magnification, ×200). (B) Typically, the lumen or cavity in the tumor cytoplasm contain single or multiple erythrocytes (magnification, ×200). (C) Tumor cells are rich in certain areas, with marked atypia. The tumor cells are arranged in solid nests and duct-like structures, and form papillary structures in the blood vessels (magnification, ×200). (D) Tumor cells show multiple small nodules and local cerebral calcification at the necrotic center (magnification, ×100).