. 2014 Apr 10;25(11):2499–2510. doi: 10.1681/ASN.2013070786

Table 1.

Summary of body weight, organ weights, blood, and kidney function parameters in FHH and Nr4a1^−/− rats at weeks 8, 16, and 24

Trait	Week 8		Week 16		Week 24
Trait	FHH Rats	Nr4a1^−/− Rats	FHH Rats	Nr4a1^−/− Rats	FHH Rats	Nr4a1^−/− Rats
Body weight (g)	207±3.1	190±2.6^a	352±5.8	328±5.2^a	429±9.5	352±14.0^a
Kidney weight (mg/g)	9.2±0.27	10.3±0.14^a	9.2±0.27	10.3±0.14^a	8.1±0.18	11.0±0.53^a
Heart weight (mg/g)	3.7±0.23	3.9±0.8	3.7±0.23	3.9±0.8	3.1±0.06	3.4±0.13
Liver weight (mg/g)					35.6±0.73	42.7±1.56^a
Drinking volume (ml)	48±4.0	38±3.4	36±6.2	28±4.4	20±5.0	22±2.4
Urine volume (ml)	47±3.4	37±2.1	39±5.3	31±3.7	24±3.7	24±2.1
Albuminuria (mg/24 h per 100 g body wt)	0.6±0.09	8±2.3.5^a	12±6.1	32±5.5^a	17±3.6	52±5.8^a
Creatinine clearance (ml/min per g kidney weight)	1.2±0.07	1.0±0.12	0.9±0.06	0.7±0.06	1.2±0.2	0.6±0.2^a
BUN (mg/dl)	14±1.5	14±0.6	14±0.6	17±0.6^a	14±1.6	23±1.6^a
Cholesterol	70±4.7	71±2.1	84±7.9	122±8.7^a	102±9.7	283±29.4^a
Triglycerides	32±1.4	30±3.0	37±5.3	82±12.6^a	50±4.4	192±43.3^a

P<0.05.