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. 2014 Oct 30;10(10):e1003880. doi: 10.1371/journal.pcbi.1003880

Figure 1. Workflow of FamSeq.

Figure 1

We use a pedigree file and a file that includes the likelihood (Inline graphic) as the input to estimate the posterior probability (Inline graphic) for each variant genotype. (E-S: Elston-Stewart algorithm; BN: Bayesian network method; BN-GPU: The computer needs a GPU card installed to run the GPU version of the Bayesian network method; MCMC: Markov chain Monte Carlo method; VCF: variant call format.)