Table 1. Model parameters.

Parameter	Realistic Value	Description	Reference
n	1–8	Number of epitopes recognized during first 100 days	[11], [13], [30], [31]
m	2–10	Number of sites per epitope important for recognition	[11], [13], [30], [31]
	1	Rate at which activated target cells transition out of the highly infectable phase	[46], [68]
	cells	Activated target cell level	[47], [69], [70]
	1	Virus-induced infected cell death rate	[55]
	4	CTL-induced infected cell death rate	[47], [69], [70]
β		Basic efficiency of target cell infection	[47], [69], [70]
s		Intrinsic mutation cost	[10], [21], [22], [27]–[29]
α		Reduction of CTL recognition	[27]–[29]
		Fractional reduction in intrinsic replication rate
		Fractional reduction of CTL recognition
		CTL killing efficiency. Gives CTLs in chronic infection	[45]
	cells	Initial population of CTLs	[69]
c	1	Maximum growth rate of effector cells	[69]
	0.1	Death rate of effector cells	[47], [69], [70]
	cells	Number of recognized infected cells for half maximal proliferation of CTL (inverse avidity). Gives an infected cell level of in chronic infection	[44]

Model parameters for the model of escape from multiple CTL shown in Figure 1.