Table 2.
Number of Opioid Prescriptions for Opioid-Naive Inpatients, According to Renal Function
| Opioid | Renal Impairment*; No. of Prescriptions | |||
|---|---|---|---|---|
|
| ||||
| Mild | Moderate | Severe | Total | |
| Hydromorphone (PO, IV, SC) | 74 | 33 | 3 | 110 |
| Morphine (PO, IV, SC) | 79 | 12 | 1 | 92 |
| Percocet (acetaminophen 325 mg, oxycodone 5 mg) | 8 | 6 | 0 | 14 |
| Oxycodone | 5 | 1 | 0 | 6 |
| Codeine (PO only) | 0 | 1 | 0 | 1 |
| Tylenol | ||||
| No. 3 (acetaminophen 300 mg, caffeine 15 mg, codeine 30 mg) | 16 | 2 | 0 | 18 |
| No. 2 (acetaminophen 300 mg, caffeine 15 mg, codeine 15 mg) | 2 | 3 | 0 | 5 |
| No. 1 (acetaminophen 300 mg, caffeine 8 mg, codeine 8 mg) | 1 | 0 | 0 | 1 |
| Total | 185 | 58 | 4 | 247 |
IV = intravenous, PO = by mouth, SC = subcutaneous.
*
Renal impairment was defined in terms of creatinine clearance, as follows: mild = creatinine clearance ≥ 50 mL/min; moderate = creatinine clearance 10–49 mL/min; severe = creatinine clearance < 10 mL/min.