Table 3.

Examples of Topic Diversity

Topic	Quoted Example
Patient-specific therapeutic questions	I was wondering if anyone could offer some advice on the use of nortriptyline in a patient with AFib? We have a morbidly obese [patient] with multiple issues. He has AFib and is describing pain in his feet that may be related to diabetic neuropathy. He also has some issues with difficulty sleeping. We are thinking of trying [nortriptyline] 10 mg qhs (titrate to 50 mg qhs) to help with the neuropathy (among other strategies for contributing factors) with the potential for a beneficial influence on his sleep. However, he also has AFib. I’m not sure how concerned to be about the potential cardiac toxicity that could be associated with TCAs. Does anyone have experience using [nortriptyline] in someone with AFib? Any particular monitoring you would recommend?
Medication indication	Has anyone come across the use of low dose Naltrexone for Crohn’s disease?
Medication availability	Anyone know anything about a shortage of allopurinol? We are getting faxes from local community pharmacies that they cannot get any. Is this a national issue? What is the problem?
Practice management needs	I am looking to see if there are any templates out there that you have found useful in conducting a medication review.
Provision of information (unsolicited)	For those interested, here is the recent “early” release of the Clinical Practice Guidelines for Osteoporosis. Officially just launched at the ASBMR meeting in Toronto this week.

AFib = atrial fibrillation, ASBMR = American Society for Bone and Mineral Research, TCA = tricyclic antidepressant.