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List of upregulated master regulators for each GBM subtype.
| CLASSICAL | NEURAL | MESENCHYMAL | PRONEURAL− | PRONEURAL+ |
|---|---|---|---|---|
| AEBP1 | BUD31 | AEBP1 | BUD31 | CTDSP1 |
| BUD31 | CEBPB | BUD31 | EN2 | DMTF1 |
| CEBPD | EN2 | EN2 | HES6 | EBF1 |
| EN2 | FOXJ1 | HEYL | HEYL | HES6 |
| FOXJ1 | HES6 | HNF4G | HOXD11 | PHC1 |
| HES6 | HNF4G | LEF1 | LEF1 | SIX4 |
| HOXD11 | LEF1 | LITAF | LITAF | UXT |
| LEF1 | LITAF | LTF | LTF | ZNF227 |
| LITAF | LTF | NMI | NMI | ZNF85 |
| LTF | NMI | PRIC285 | RUNX1 | |
| PRIC285 | PCGF1 | RUNX1 | SHOX2 | |
| RUNX1 | RUNX1 | SHOX2 | SNAI2 | |
| SNAI2 | SNAI2 | SNAI2 | SPI1 | |
| SP100 | SP100 | SP100 | TEAD3 | |
| SPI1 | UXT | SPI1 | UXT |
