Table 2.
List of downregulated master regulators for each GBM subtype.
| CLASSICAL | NEURAL | MESENCHYMAL | PRONEURAL− | PRONEURAL+ |
|---|---|---|---|---|
| CHD3 | ARID4A | CHD3 | DACH2 | ARNTL2 |
| DACH2 | CHD3 | DACH2 | EZH1 | KLF16 |
| EZH1 | DACH2 | EZH1 | IKZF5 | LZTFL1 |
| IKZF5 | EZH1 | IKZF5 | KLF16 | MEF2A |
| KLF13 | IKZF5 | JMY | MMS19 | NPAS2 |
| LCOR | JMY | KLF13 | MTA3 | NR3C2 |
| LDB1 | KLF13 | LDB1 | NCOA1 | PCGF5 |
| MMS19 | LCOR | MTA3 | NPAS2 | PHF15 |
| MTA3 | LDB1 | MYST4 | NR3C2 | PLAGL1 |
| NR3C2 | MTA3 | NCOA1 | PHF15 | RNF14 |
| TCEAL7 | MYST4 | NR3C2 | TCEAL7 | SATB2 |
| TIAM1 | SUDS3 | TIAM1 | TIAM1 | STAT6 |
| ZMYND11 | ZMYND11 | ZMYND11 | ZMYND11 | TCEAL7 |
| ZNF208 | ZNF208 | ZNF248 | ZNF208 | TFPT |
| ZNF248 | ZNF248 | ZNF248 | TLE4 |