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. 2014 Oct 30;10(10):e1004751. doi: 10.1371/journal.pgen.1004751

Figure 7. WWP2 suppresses tumor development of ovarian cancer cells.

Figure 7

(A) Tumorigenic SKOV3-CR cells were transfected with either the plasmid encoding WWP2 cDNA or the control plasmid, pLPC. The expression of WWP2 was determined by Western blot. (B) Cells were injected into the right flanks of athymic nu/nu mice. The tumor size was measured by a caliper every three days. Two-tailed Student's t-test was used to determine the significance level. ** p<0.01; *** p<0.001 (C) Tumor weight was measured at the end point. Two-tailed Student's t-test was employed to determine the significance level.