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. 2014 Oct 30;9(10):e110758. doi: 10.1371/journal.pone.0110758

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© 2014 Plat et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Scoring for the size and foamy appearance of Kupffer cells using CD68 staining. (B) Scoring for the size and foamy appearance of Kupffer cells using HE staining. A score ranging from 0–3 was given by an experienced pathologist. (C) Representative pictures of the foamy Kupffer cell appearance with CD68 staining (200x magnification). *P<0.05, **P<0.01, and ***P<0.001, respectively.