Table 3. Genes that were more expressed (P<0.05) in OXY mucosa, a priori selected for their relevance in the stomach, compared with PYL mucosa1.
| Gastric mucosa2 | ||||
| Gene product | Gene name | OXY | PYL | SEM |
| Acid secretion and pH homeostasis | ||||
| H+/K+ Atpase α | ATP4A | 12.1 | 4.6 | 0.09 |
| Anion exchanger 2 | SLC4A2 | 10.0 | 7.9 | 0.12 |
| Ion and water channels | ||||
| Potassium voltage-gated channel, Isk-related family, member 2 | KCNE2 | 10.2 | 3.9 | 0.20 |
| Potassium inwardly rectifying channel, subfamily J, member 13 | KCNJ13 | 8.0 | 3.3 | 0.27 |
| Potassium inwardly rectifying channel, subfamily J, member 15 | KCNJ15 | 8.8 | 3.7 | 0.17 |
| Chloride intracellular channel 6 | CLIC6 | 10.7 | 4.0 | 0.14 |
| Aquaporin 4 | AQP4 | 9.5 | 3.0 | 0.26 |
| Endocrine mediators, growth factors, receptors and binding proteins | ||||
| Insulin-like growth factor binding protein 5 | IGFBP5 | 10.1 | 8.5 | 0.25 |
| Ghrelin/Obestatin Prepropeptide | GHRL | 9.9 | 7.8 | 0.38 |
| Epidermal growth factor | EGF | 9.4 | 5.1 | 0.41 |
| Digestive enzymes, nutrient uptake and transport | ||||
| Pepsinogen B | PGB | 11.9 | 10.4 | 0.13 |
| Pepsinogen C | PGC | 12.2 | 11.3 | 0.14 |
| Chitinase, acidic | CHIA | 12.2 | 7.8 | 0.19 |
| Lipoprotein lipase | LPL | 9.8 | 7.6 | 0.46 |
| Solute carrier family 2 (facilitated glucose transporter), member 4 | SLC2A4 | 8.7 | 6.4 | 0.36 |
| Others | ||||
| Alcohol dehydrogenase, iron containing, 1 | ADHFE1 | 6.9 | 5.6 | 0.32 |
1
OXY = oxyntic mucosa; PYL = pyloric mucosa.
2
Mean values, expressed as log2 of intensity values.