Table 1.
Incidence of CBF-AML, as well as the cytogenetic subgroups of inv(16) AML, and t(8;21) AML, diagnosed between 2000-2010 in patients 15-84 years old at diagnosis. The incidence of all sub-types of AML reported to SEER is included as a reference.
AML (all subtypes) | CBF-AML | inv(16) subgroup | t(8;21) subgroup | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No. of patients | Incidence rate† | No. of patients | Incidence rate† | Median age at diagnosis | No. of patients | Incidence rate† | Median age at diagnosis | No. of patients | Incidence rate† | Median age at diagnosis | |
All patients, 15-84 yr. | 27665 | 4.11 | 777 | 0.11 | 54 | 320 | 0.05 | 50 | 457 | 0.07 | 57 |
Age Group | |||||||||||
15-44 yr. | 4811 | 1.24 | 254 | 0.06 | 31 | 128 | 0.03 | 33 | 126 | 0.03 | 28 |
45-64 yr. | 8584 | 3.81 | 285 | 0.13 | 54 | 115 | 0.05 | 55 | 170 | 0.08 | 53 |
65-74 yr. | 6659 | 12.35 | 137 | 0.25 | 69 | 46 | 0.08 | 69 | 91 | 0.17 | 69 |
75-84 yr. | 7611 | 20.87 | 101 | 0.28 | 79 | 31 | 0.09 | 77 | 70 | 0.19 | 80 |
Gender | |||||||||||
Male | 15209 | 4.99 | 441 | 0.14 | 56 | 186 | 0.06 | 51 | 255 | 0.08 | 60 |
Female | 12456 | 3.43 | 336 | 0.09 | 51 | 134 | 0.04 | 49 | 202 | 0.06 | 52 |
Race†† | |||||||||||
White | 23132 | 4.26 | 632 | 0.12 | 56 | 277 | 0.05 | 52 | 355 | 0.06 | 59 |
Black | 2305 | 3.40 | 57 | 0.07 | 52 | 12 | 0.02 | 46 | 45 | 0.06 | 52 |
Other | 2102 | 3.23 | 87 | 0.12 | 47 | 31 | 0.04 | 41 | 56 | 0.08 | 49 |
Ethnicity | |||||||||||
Non-Hispanic | 24632 | 4.18 | 673 | 0.11 | 56 | 269 | 0.05 | 52 | 404 | 0.07 | 58 |
Hispanic | 3033 | 3.44 | 104 | 0.09 | 44 | 51 | 0.04 | 39 | 53 | 0.05 | 46 |
Incidence rate was adjusted to the US 2000 standard population and is per 100 000 people
Other includes American Indian, Alaska Native, Asian, or Pacific Islander. The patient in CBF AML (n=1) and overall AML (n=126) with unknown race is not listed.