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. 2014 Oct 30;9(10):e111819. doi: 10.1371/journal.pone.0111819

Figure 2. Venn diagrams of protease and protease inhibitor genes upregulated in both GBM tissue and GBM cells.

Figure 2

In total, 669 protease and 242 protease inhibitor genes were checked for deregulation in GBM tissues and cells in comparison to non-malignant brain tissue and NHA cells. Venn diagrams include upregulated genes in GBM tissues and cells with PFP >0.05. Candidate genes appear in the intersections of Venn diagrams. Comparisons of protease genes upregulated in GBM tissue and in U87-MG cells (A) and upregulated in GBM tissue and in U373 cells (B) across Illumina and Affymetrx platforms and within the Affymetrix platform only are shown. The other 2 Venn diagrams show comparisons of protease inhibitor genes upregulated in GBM and in U87-MG cells (C) and upregulated in GBM and in U373 cells (D) across Illumina and Affymetrx platforms and within the Affymetrix platform only.