Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for the role of APC self-association in promoting Axin puncta formation. (A) Normal Axin polymers form via the weak DAX interactions (thin lines) in the absence of APC. (B) Larger Axin polymers form via the stronger interaction between APC's SAMP repeats and Axin's RGS domains (thick lines) due in part to APC's ability to self-associate (unknown binding affinity; wavy lines). (C) Smaller Axin polymers form in the absence of APC self-association.
