Table 2. Body fat mass ratio, lean mass ratio, absolute lean mass weight and caloric intake of mice¹.

	Treatment				p value
	AIN WT	AIN PAI-1−/−	HF WT	HF PAI-1−/−	Diet	Gene	Diet × Gene
Fat mass ratio, %	19.0±0.8	16.8±1.3	27.9±1.5	23.1±1.3	<0.01	<0.01	0.29
Lean mass ratio, %	72.0±0.8	73.9±1.1	64.1±1.4	68.3±1.1	<0.01	<0.01	0.32
Lean mass weight, g	21.1±0.3	21.9±0.4	21.8±0.3	22.2±0.4	0.12	0.07	0.45
Caloric intake, kCal/day	16.1±0.3	14.6±0.5	17.3±0.6	15.9±0.7	<0.05	<0.05	0.92

¹Two-way ANOVA was performed to test for differences among the groups. Values are means ± SEM (n = 22 per group for PAI-1^−/− mice, n = 28 per group for wild-type mice or n = 6 per group for caloric intake). AIN WT: AIN93G-fed wild-type mice, AIN PAI-1^−/−: AIN93G-fed PAI-1^−/− mice, HF WT: high-fat fed wild-type mice, HF PAI-1^−/−: high-fat fed PAI-1^−/− mice.