Table 1.

Body mass and renal function measurements

	SHAM	SED	ARG	RUN	RUN+ARG
Body mass, g	432 ± 9	376 ± 13*	376 ± 18*	402 ± 9	388 ± 17
Urine protein excretion, mg·24 h−1·100 g−1 BM
Baseline	6.2 ± 0.7	5.3 ± 0.8	5.8 ± 0.5	6.2 ± 0.7	7.2 ± 1.5
Week 4	4.5 ± 0.8	42.4 ± 5.8†	50.3 ± 12.2†	35.7 ± 4.5†	41.4 ± 7.0†
Week 8	6.0 ± 0.8	51.7 ± 6.1†	48.4 ± 9.4†	53.5 ± 6.7†	65.5 ± 7.1†
Creatinine clearance, ml·min−1·100 g BM−1	1.2 ± 0.42	0.34 ± 0.09*	0.26 ± 0.11*	0.20 ± 0.09†	0.22 ± 0.07†
BUN, mg/dl	25.5 ± 0.9	72.15 ± 2.5*	71.5 ± 2.1*	69.3 ± 2.6*	68.3 ± 4.5*

Values are mean ± SE.

BM, body mass; BUN blood urea nitrogen; SED, sedentary rats; RUN, wheel-running rats; ARG, l-arginine-treated rats.

^*P < 0.05 vs. SHAM.

^†P < 0.001 vs. SHAM; n = 5–8/group.