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Effects of HET0016, rofecoxib, and rofecoxib + HET0016 on cell numbers (A) and BrdU incorporation in NCM460 cells (B). NCM460 cells were treated with HET0016 (1 μM), rofecoxib (1 μM), HET0016 (1 μM) + rofecoxib (1 μM), or vehicle for 48 h. A: cell proliferation by counting cell numbers was determined as described in Fig. 3. B: BrdU incorporation was determined using an ELISA kit as described in Fig. 4. Values are means ± SE; n = 4 (A), n = 5 (B).
