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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Transl Stroke Res. 2014 Sep 13;5(6):660–668. doi: 10.1007/s12975-014-0368-4

Table 3.

Advantages/Limitations/Disadvantages

Advantages Limitations
Replicates the mechanical trauma experienced by the brain and cerebral vasculature Requires extensive complicated surgery
Replicates events observed during rebleed in SAH patients:
  • Rapid ICP and MABP rise and CBF and CPP fall

  • Blood accumulation into subarachnoid space

Poor control of bleeding and hemorrhage severity
Allows real time recording of early physiological changes after SAH Lacks proper control
High mortality