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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Clin Pharmacokinet. 2014 Nov;53(11):989–1004. doi: 10.1007/s40262-014-0185-7

Table 3. IC50 values for wild-type HIV for select antiretroviral agents [109, 110, 111].

Converted from original molar concentrations to mg/L for ease of comparison with cord data.

Antiretroviral Drug IC50 (mg/L) [109]*
Zidovudine 0.0053
Lamivudine 0.55
Didanosine 1.18
Stavudine 0.11
Abacavir 0.46
Tenofovir 0.20
Nevirapine 0.024
Efavirenz 0.00051
Indinavir 0.0037
Nelfinavir 0.0032
Saquinavir 0.0017
Lopinavir 0.0019
Atazanavir [110] No AAG: 0.0049
With AAG: 0.047
Raltegravir [111] 0.0036
*

From this reference except where otherwise specified.

AAG = α-1-acid glycoprotein, a drug-binding protein