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. Author manuscript; available in PMC: 2014 Oct 30.
Published in final edited form as: World J Immunol. 2014 Mar 27;4(1):1–11. doi: 10.5411/wji.v4.i1.1

Figure 2. Stimulation of adaptive anti-tumor immunity by photodynamic therapy.

Figure 2

PDT-treated tumor cells release the antigens, which are phagocytosed by DCs and presented to naive T cells in the tumor draining lymph node. Activated effector T cells return in circulation and migrate to the tumor. Regulatory T cells seem to inhibit the immune responses after PDT. DCs: Dendritic cells; Hv: Light; MHC I : Major histocompatibility class I ; PDT: Photodynamic therapy. Original figure based upon Ref. [115] and Ref. [116].