Enzyme-linked immunosorbent assay analysis of soluble C5b-9 MAC in young eyes, aged eyes without AMD (control), and eyes with atrophic AMD. Increased MAC levels were related to increased age (∗∗∗P < 0.001) and to diagnosis of AMD (∗P < 0.05). Data are expressed as box-and-whisker plots, indicating median, interquartile range, and minimum and maximum values; any outliers are indicated by individual symbols. n = 10 per group. AMD, age-related macular degeneration; Ctl, control; MAC, membrane attack complex.