Table 2.
Characteristics of Donor Eyes Used for Immunohistochemistry
| Donor ID | Age (years) | AMD Dx | Cause of death | D–P time (hours) |
|---|---|---|---|---|
| 1 | 0 | None | Cardiac arrest | 7:00 |
| 2 | 1 | None | Cardiac arrest | 7:00 |
| 3 | 5 | None | Myelogenous leukemia | 8:06 |
| 4 | 21 | None | Hemorrhagic pancreatitis/leukemia | 5:23 |
| 5 | 21 | None | Hodgkin lymphoma | 6:03 |
| 6 | 28 | None | Metastatic carcinoma | 4:12 |
| 7 | 41 | None | Ovarian cancer | 4:50 |
| 8 | 42 | None | Anaplastic T-cell lymphoma/sepsis | 4:12 |
| 9 | 48 | None | Septic shock | 5:53 |
| 10 | 50 | None | Adenocarcinoma/respiratory failure | 7:35 |
| 11 | 53 | None | Cardiac arrest | 6:30 |
| 12 | 57 | None | Cardiogenic shock/heart disease | 5:50 |
| 13 | 59 | None | Lymphoma | 4:59 |
| 14 | 60 | None | Sepsis | 7:45 |
| 15 | 62 | None | Cardiac arrest | 7:18 |
| 16 | 63 | None | Myocardial infarction | 5:06 |
| 17 | 65 | None | Renal failure | 4:56 |
| 18 | 66 | None | Unknown | 6:32 |
| 19 | 67 | None | Lung cancer | 4:22 |
| 20 | 67 | None | Sepsis | 5:50 |
| 21 | 68 | AMD: OS GA | NA | 6:48 |
| 22 | 68 | None | Acute leukemia | 6:57 |
| 23 | 69 | AMD: OU dry | Respiratory failure | 7:22 |
| 24 | 70 | AMD: OU wet | NA | 3:54 |
| 25 | 70 | None | Acute respiratory failure | 5:57 |
| 26 | 70 | AMD: OD CNV | Cardiac arrest | 7:50 |
| 27 | 71 | None | Sepsis | 7:02 |
| 28 | 72 | None | Perforated bowel | 5:03 |
| 29 | 73 | None | Throat cancer | 5:45 |
| 30 | 74 | None | Ovarian cancer | 7:25 |
| 31 | 75 | None | NA | 5:15 |
| 32 | 76 | AMD: OU dry | Subdural hematoma | 4:44 |
| 33 | 76 | AMD: OU dry | Basal ganglion bleed | 6:01 |
| 34 | 76 | None | NA | 7:38 |
| 35 | 76 | AMD: OU dry | NA | 8:03 |
| 36 | 77 | None | Brain tumor | 5:07 |
| 37 | 77 | AMD: OD wet, OS dry | NA | 5:58 |
| 38 | 77 | AMD: OU dry | Sepsis | 6:35 |
| 39 | 77 | None | Aortic valve stenosis/congestive heart failure | 6:41 |
| 40 | 78 | AMD: OD dry | Respiratory failure 2 COPD | 4:07 |
| 41 | 78 | AMD | Respiratory failure | 4:56 |
| 42 | 78 | AMD: OU dry | Subarachnoid hemorrhage | 5:34 |
| 43 | 78 | None | Sepsis | 5:47 |
| 44 | 79 | None | Metastatic lung cancer | 4:50 |
| 45 | 79 | None | NA | 5:32 |
| 46 | 79 | None | Bladder cancer | 5:52 |
| 47 | 79 | None | NA | 6:26 |
| 48 | 79 | AMD: OU dry | NA | 6:47 |
| 49 | 79 | AMD: OD dry, OS wet | Lymphoma | 7:55 |
| 50 | 79 | AMD: OU dry | NA | NA |
| 51 | 80 | None | NA | 4:51 |
| 52 | 80 | AMD: OD dry | COPD | 4:53 |
| 53 | 80 | None | NA | 5:34 |
| 54 | 80 | None | Hemorrhagic shock | 8:00 |
| 55 | 81 | None | Cancer | 4:44 |
| 56 | 81 | None | NA | 6:02 |
| 57 | 81 | None | Renal failure | 6:30 |
| 58 | 82 | None | Respiratory failure | 5:12 |
| 59 | 82 | AMD: OU GA | Respiratory failure | 6:04 |
| 60 | 82 | None | Perforated bowel | 6:52 |
| 61 | 82 | None | Multisystem cancer | 8:20 |
| 62 | 83 | AMD: OU GA | NA | 5:24 |
| 63 | 83 | AMD: OU dry | Motor vehicle collision | 5:55 |
| 64 | 83 | None | NA | 6:32 |
| 65 | 83 | AMD: OU wet | Myocardial infarction | 8:40 |
| 66 | 84 | AMD: OU dry | Respiratory failure | 4:16 |
| 67 | 84 | None | Hypoxia due to congestive heart failure | 5:43 |
| 68 | 85 | None | NA | 6:56 |
| 69 | 86 | AMD: OU dry | NA | 3:13 |
| 70 | 86 | AMD: OS dry | Small bowel obstruction/renal insufficiency | 3:35 |
| 71 | 86 | None | Heart disease | 6:05 |
| 72 | 86 | AMD: OU dry | Myocardial infarction | 6:54 |
| 73 | 86 | AMD: OU wet | Colon cancer | 7:20 |
| 74 | 87 | AMD: OD GA, OS wet | Heart and respiratory failure | 4:37 |
| 75 | 87 | None | NA | 5:26 |
| 76 | 87 | None | Stroke | 5:30 |
| 77 | 87 | AMD: OU dry | Motor vehicle accident with head injury | 5:42 |
| 78 | 87 | AMD: OU wet | Myocardial infarction | 5:45 |
| 79 | 87 | AMD: OU GA | Prostate cancer | 8:50 |
| 80 | 88 | None | NA | 2:35 |
| 81 | 88 | AMD: OU dry | GI bleed | 4:12 |
| 82 | 88 | None | Respiratory failure | 5:35 |
| 83 | 88 | None | Complications after a fall | 5:37 |
| 84 | 88 | None | NA | 5:56 |
| 85 | 88 | AMD: OD GA, OS wet | Heart failure | 6:43 |
| 86 | 88 | None | Respiratory failure/sepsis | 8:10 |
| 87 | 88 | None | Cardiogenic shock | 9:15 |
| 88 | 88 | AMD: OU dry | Cerebrovascular accident | NA |
| 89 | 89 | None | NA | 4:20 |
| 90 | 89 | None | Stroke | 5:08 |
| 91 | 89 | AMD: OU dry | Congestive heart failure | 7:10 |
| 92 | 90 | None | Cardiac arrest | 4:27 |
| 93 | 90 | AMD: OD wet, OS dry | Cerebrovascular accident | 5:30 |
| 94 | 90 | None | Cerebrovascular accident | 6:46 |
| 95 | 90 | None | NA | 8:50 |
| 96 | 91 | None | Cerebrovascular accident | 5:06 |
| 97 | 91 | AMD: OD wet, OS early dry | NA | 5:10 |
| 98 | 91 | None | NA | 5:32 |
| 99 | 91 | AMD: OU dry | Aspiration pneumonia | 7:48 |
| 100 | 91 | AMD: OU wet | Intracerebral hemorrhage | NA |
| 101 | 92 | AMD: OU dry | Acute myocardial infarction | 4:25 |
| 102 | 92 | AMD: OU dry | Lung cancer | 5:25 |
| 103 | 92 | AMD: OU dry | Cardiac arrest | 7:49 |
| 104 | 93 | None | Respiratory failure | 5:50 |
| 105 | 93 | AMD: OU dry | Renal insufficiency | 6:30 |
| 106 | 94 | None | Congestive heart failure | 5:34 |
| 107 | 94 | None | Respiratory failure | 5:34 |
| 108 | 94 | AMD: OU dry | Cardiac arrest | 5:46 |
| 109 | 94 | AMD: OU dry | Cardiac arrest | 7:40 |
| 110 | 95 | AMD: OD GA | Stroke/atrial fibrillation | 6:20 |
| 111 | 95 | AMD: OU dry | Heart and renal failure | 6:35 |
| 112 | 96 | AMD: OU dry | NA | 5:00 |
| 113 | 98 | None | NA | 5:41 |
| 114 | 98 | AMD: OU dry | COPD | 6:14 |
| 115 | 98 | AMD: OU dry | Multisystem organ failure/renal failure | 6:17 |
| 116 | 99 | AMD: OD GA | NA | 1:42 |
| 117 | 100 | AMD: OD dry | Found unresponsive | 5:55 |
CNV, choroidal neovascularization; COPD, chronic obstructive pulmonary disease; D–P, maximum time between death and preservation in liquid nitrogen or fixative; Dx, diagnosis; GA, geographic atrophy; GI, gastrointestinal tract; NA, not available; OD, right eye; OS, left eye; OU, both eyes.