Figure 2.

Heat maps demonstrate technical feasibility of microarray-based transcriptome analyses on LCM samples. A: Heat map of differentially expressed (DE) gene transcripts from LCM T versus NT lung specimens. A total of 850 genes with adjusted P value < 0.05 and log₂ fold change (FC) of ≥1.0 were used for this comparison. B: A similar heat map differentiates LCM adenocarcinomas from LCM squamous cell carcinomas. A total of 651 genes with adjusted P < 0.05 and log₂ FC ≥ 1.0 were used for this comparison.