Table 1.
Demographic and Clinical Characteristics of the Study Population With or Without Latent Mycobacterium tuberculosis Infection
| Characteristic | Latent Infection, Plus |
No Latent Infection, Plus |
|||
|---|---|---|---|---|---|
| DM (n = 30) | Pre-DM (n = 30) | No DM (n = 30) | DM (n = 30) | No DM (n = 30) | |
| Male sex | 17 | 11 | 11 | 14 | 12 |
| Age, y, median (range) | 45.5 (28–65) | 43.3 (23–65) | 33.7 (19–60) | 45 (21–64) | 35.5 (20–54) |
| Height, m, median (range) | 1.565 (1.35–1.84) | 1.53 (1.37–1.76) | 1.535 (1.4–1.79) | 1.56 (1.35–1.79) | 1.52 (1.39–1.78) |
| Weight, kg, median (range) | 61 (50–99) | 58 (34–87) | 52.5 (28–92) | 58 (28–92) | 62 (34–87) |
| Body mass indexa | 25.89 (19.92–37.39) | 24.39 (15.50–31.11) | 22.55 (12.28–33.33) | 23.49 (12.28–30.85) | 26.14 (16.11–33.33) |
| Mantoux skin test, induration diameter, mmb | >12 | >12 | >12 | <12 | <12 |
| IFN-γ–release assay result | Positive | Positive | Positive | Negative | Negative |
| Random blood glucose level, mg/dL | 200 (71–537) | 101 (60–226) | 94 (64–139) | 144 (100–370) | 87 (71–128) |
| Glycated Hb level, % | 8.92 (6.53–13.13) | 6.2 (6.07–6.38) | 5.1 (4.57–5.36) | 7.90 (6.53–11.74) | 5.24 (4.63–5.42) |
| AST level, U/L | 24.4 (14–46) | 23.7 (12–58) | 22.1 (10–31) | 24.5 (13–50) | 21 (11–41) |
| ALT level, U/L | 23.7 (10–67) | 20.8 (10–77) | 15.8 (6–35) | 22 (10–67) | 15 (9–34) |
| Urea level, mg/dL | 22.7 (15–49) | 20.3 (12–35) | 19 (11–30) | 20.5 (11–38) | 20.5 (8–38) |
| Creatinine level, mg/dL | 0.83 (0.6–1.3) | 0.73 (0.5–1.1) | 0.77 (0.3–0.9) | 0.75 (0.6–1.2) | 0.8 (0.3–1.2) |
Data are geometric means (range), unless otherwise indicated.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; DM, diabetes mellitus type 2; Hb, hemoglobin; IFN-γ, interferon γ.
a Defined as the weight in kilograms divided the height in square meters.
b An induration diameter of >12 mm was considered positive.