Table 4. The correlation analyses between the expressions of tumor marker genes and the clinicopathological characteristics.
| Characteristics | No. | CA125 | P value | CYFRA21-1 | P value | NSE | P value | SCC | P value |
|---|---|---|---|---|---|---|---|---|---|
| Gene | MUC16 | KRT19 | ENO2 | SERPINB3 | |||||
| Age | 0.176 | 0.21 | 0.375 | 0.213 | |||||
| ≥60 | 26 | 1.624±3.015 | 1,898±1,734 | 43.90±33.51 | 19.18±42.76 | ||||
| <60 | 18 | 3.237±4.775 | 2,619±2,004 | 34.27±37.07 | 37.29±52.04 | ||||
| Smoking status | 0.314 | 0.52 | 0.7 | 0.14 | |||||
| Yes | 23 | 2.852±4.119 | 2,018±1,756 | 41.93±29.06 | 36.65±51.38 | ||||
| No | 21 | 1.662±3.577 | 2,385±1,995 | 37.80±41.01 | 15.57±40.35 | ||||
| Primary tumor | 0.368 | 0.274 | 0.003 | 0.577 | |||||
| T1 | 15 | 1.091±2.662 | 2,127±1,627 | 28.36±27.48 | 15.25±33.28 | ||||
| T2 | 19 | 3.039±4.473 | 2,206±2,186 | 42.64±34.62 | 37.33±60.62 | ||||
| T3 | 6 | 2.958±3.496 | 2,157±1,487 | 46.96±33.21 | 16.97±27.52 | ||||
| T4 | 4 | 2.218±4.438 | 2,433±1,748 | 60.23±50.28 | 32.53±31.55 | ||||
| Regional lymph nodes | 0.897 | 0.792 | 0.288 | 0.196 | |||||
| N0 | 29 | 1.940±3.147 | 1,960±1,952 | 37.06±30.68 | 24.55±41.68 | ||||
| N1 | 8 | 1.607±1.717 | 2,886±1,517 | 57.54±43.53 | 20.57±42.28 | ||||
| N2 | 7 | 4.486±6.788 | 2,367±1,750 | 31.90±36.42 | 41.93±68.70 | ||||
| Differentiation | 0.708 | 0.207 | 0.765 | 0.361 | |||||
| Well differentiated | 8 | 2.588±3.340 | 1,967±1,664 | 35.97±28.64 | 20.97±32.79 | ||||
| Moderately differentiated | 18 | 2.414±4.726 | 1,992±1,583 | 34.58±30.47 | 33.57±60.98 | ||||
| Poorly differentiated | 18 | 2.019±3.162 | 2,492±2,186 | 47.11±40.88 | 22.11±33.55 | ||||
| TNM stage | 0.389 | 0.757 | 0.172 | 0.082 | |||||
| I | 23 | 2.165±2.975 | 2,186±2,035 | 34.79±29.56 | 21.98±40.26 | ||||
| II | 12 | 2.337±3.117 | 2,432±1,578 | 44.03±40.92 | 26.47±40.16 | ||||
| III | 9 | 2.517±6.270 | 1,892±1,807 | 47.75±38.54 | 38.53±67.80 |