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. 2014 Nov 1;28(21):2348–2360. doi: 10.1101/gad.250902.114

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© 2014 Alcid and Tsukiyama; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 6. — Identification of ASlncRNAs whose repression by chromatin remodeling factors is required for the maintenance of the normal level of overlapping mRNAs. (A) Changes in the levels of Isw2-repressed CRRATs (dark blue) and overlapping mRNAs (light blue) in itc1 cells. The solid lines denote the mean, and the colored ribbon shows the RNA signals of the top 25% and bottom 25% values in the mutants. RNAs are aligned at the TSSs of mRNAs (left panel) and the TSSs of CRRATs (right panel). The Y-axis is in log₂ scale, and a dotted line is at the value 0. (B) Changes in the levels of Rsc-repressed CRRATs (red) and overlapping mRNAs (light blue) in tet-STH1 cells. The solid lines denote the mean, and the colored ribbon shows the RNA signals of the top 25% and bottom 25% values in the mutants. RNAs are aligned at the TSSs of mRNAs (left panel) and the TSSs of CRRATs (right panel). The Y-axis is in log₂ scale, and a dotted line is at the value 0. (C) Changes in the levels of Ino80-repressed CRRATs (green) and overlapping mRNAs (light blue) in tet-INO80 cells. The solid lines denote the mean, and the colored ribbon shows the RNA signals of the top 25% and bottom 25% values in the mutants. RNAs are aligned at the TSSs of mRNAs (left panel) and the TSSs of CRRATs (right panel). The Y-axis is in log₂ scale, and a dotted line is at the value 0.