TABLE 1.

List of candidate maxillary arch enhancers selected for functional tests

Enhancer name	Nearest gene (TSS)	Enrichment found in ChIP-seq				Result of functional test
		Human ESC-derived NCCa		Mouse E11.5 whole faceb, P300	Mouse E11.5 maxillary arch, H3K27Ac	VISTA Enhancer Browser, in vivo transgenic	This study
		P300	H3K27Ac				Primary culture	In vivo transgenic
Abca4_enh	Abca4	Yes	Yes	Yes	Yes	+	+
Chd7_enh	Chd7	No	Yes	No	Yes		−
Mafb_enh	Mafb	No	No	Yes	Yes	−	−
Myh9_enh	Txn2	No	No	No	Yes		+
Pax9_enh	Pax9	No	No	No	Yes		+
Ror2_enh	Ror2	Yes	Yes	Yes	Yes		+	+
Tgfbr2_enh1	Tgfbr2	No	No	Yes	Yes		+
Tgfbr2_enh2	Tgfbr2	No	No	No	Yes		+
Lhx8_enh1	Lhx8	No	No	No	Yes		+	+
Lhx8_enh2	Lhx8	No	No	Yes	Yes		−	−

^a Data are from Rada-Iglesias et al. (43).

^b Data are from Attanasio et al. (39).