FIGURE 7.

Vitamin K₁ postprandial response and vitamin K₁ content of mouse intestinal fragments in mice after force-feeding with a vitamin K₁-enriched emulsion. A, effect of SR-BI overexpression at the intestinal level. Four hours after force feeding with an emulsion containing 500 μg of phylloquinone, a blood sample was taken (A), and mouse intestines were harvested and cut into five fragments (B). Data are means ± S.E. (error bars); n = 8 for control mice and 8 for SR-BI transgenic (Tg) mice). B, effect of CD36 deletion (CD36 KO). Four hours after force feeding with an emulsion containing 500 μg of phylloquinone, a blood sample was taken (C), and mouse intestines were harvested and cut into five fragments (D). Data are means ± S.E.; n = 4 for control mice and 5 for CD36-deficient mice. Prox, proximal; Med, median.