Table 4.
Efficacy results at 6 and 12 months
| 6 Months | 6 Months | 12 Months | |
|---|---|---|---|
| Overall group (N=58) |
12-month follow-up group (N=34) |
12-month follow-up group (N=34) |
|
| FEV1, L | +0.11±0.20 (n=54, p<0.001) | +0.12±0.28 (n=33, p=0.021) | +0.11±0.30 (n=34, p=0.037) |
| FEV1, % pred (% change) | +15.36±26.68 (n=54, p<0.001) | +17.81±31.71 (n=33, p=0.003) | +16.04±35.54 (n=34, p=0.017) |
| FVC, L | +0.20±0.53 (n=54, p=0.008) | +0.33±0.57 (n=33, p=0.002) | +0.28±0.45 (n=34, p=0.001) |
| RV, L | −0.65±0.90 (n=58, p<0.001) | −0.80±1.03 (n=34, p<0.001) | −0.71±0.81 (n=34, p<0.001) |
| RV, % pred (% change) | −11.31±15.25 (n=58, p<0.001) | −14.38±15.42 (n=34, p<0.001) | −13.75±12.65 (n=34, p<0.001) |
| RV/TLC | −4.51±12.19 (n=58, p=0.007) | −6.06±8.58 (n=34, p<0.001) | −3.12±15.59 (n=34, p=0.245) |
| 6MWD, m | +29.7±74.1 (n=56, p=0.004) | +42.4±73.5 (n=34, p=0.002) | +51.4±76.1 (n=32, p=0.003) |
| SGRQ, points | −12.1±12.9 (n=56, p<0.001) | −10.4±15.8 (n=33, p<0.001) | −11.1±13.3 (n=32, p<0.001) |
| mMRC, points | −0.6±1.2 (n=58, p<0.001) | 0.8±0.9 (n=34, p<0.001) | −0.7±0.8 (n=34, p<0.001) |
Efficacy at 6 months for all LVR coil treatments (n=58, overall group) and at 6 and 12 months (n=34, 12-month follow-up group columns). Results are given as change from baseline. Data are shown as mean±SD.
Data in parentheses are the numbers of actual measurements available per variable tested followed by the actual p value.
6MWD, 6-min walking distance; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; mMRC, modified Medical Research Council dyspnoea score; RV, residual volume; SGRQ, St George's Respiratory Questionnaire total score; TLC, total lung capacity.