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. 2014 Oct 1;3(5):206–216. doi: 10.1089/biores.2014.0028

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Copyright 2014, Mary Ann Liebert, Inc.

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FIG. 11. — Partially reprogrammed IPSCs cultured on Matrigel. (A) Semi-thin section of partially reprogrammed IPSCs cultivated in the presence of Matrigel. The cells are round and isolated. Optical microscopy, original magnification ×400. (B) The nucleus presents heterochromatin (arrow). In the cytoplasm atypical mitochondria are often associated with rough endoplasmic reticulum (arrow). TEM, original magnification ×10,000. (C) Atypical mitochondria are gathered in a portion of cytoplasm (arrow). The nucleoplasm is of euchromatic type and the nucleolus is dense. TEM, original magnification ×10,000.