Table 1.
Baseline characteristics of FH+ versus FH− MCI subjects in ADNI.
| Attribute | FH− | FH+ | p-Value |
|---|---|---|---|
| n | 106 | 78 | |
| Age (mean) | 80.99 | 78.9 | 0.05 |
| M/F ratio | 1.58 | 1.28 | 0.56 |
| Education (years) | 15.61 | 15.48 | 0.76 |
| MMSE | 27.22 | 27.15 | 0.79 |
| MRI follow up time (months) | 27.8 | 29.5 | 0.25 |
| ApoE4 % | 0.41 | 0.65 | 0.002 |
MCI = mild cognitive impairment; FH- indicates those subjects without a family history of AD in a first degree relative; FH+ indicates those subjects with a positive family history; M/F ratio is male/female ration; MMSE is Mini-Mental State Exam; ApoE4% is percent in each group who carry the ApoE4 allele; ADNI is the Alzheimer’s Disease Neuroimaging Initiative. Refer to text for details of selection criteria.