Fig. 3.

Brain regions in which BOLD signal intensity changes correlated to muscle sympathetic nerve activity (MSNA) were significantly different in controls compared with subjects with obstructive sleep apnoea (OSA). Hot colour scale indicates regions in which signal intensity changes were greater in OSA subjects compared with controls. Significant clusters are overlaid onto a T1-weighted anatomical template image. The dark shading indicates brain regions not included in the analysis. Slice location in Montreal Neurological Institute space is indicated at the lower right of each image. ACC: anterior cingulate cortex, dlPFC: dorsolateral prefrontal cortex; mPFC: medial prefrontal cortex; RSC: retrosplenial cortex.