Fig. 5.

Brain regions in which grey matter volume (GM) was significantly different in subjects with obstructive sleep apnoea (OSA) compared with controls. Hot colour scale indicates increases in grey matter volume in OSA subjects compared with controls at a corrected statistical threshold (p < 0.05). Cool colour scale indicates decreases in grey matter volume in OSA subjects compared with controls at a more liberal uncorrected statistical threshold (p < 0.001). Significant clusters are overlaid onto a T1-weighted anatomical template image. Slice location in Montreal Neurological Institute space is indicated at the lower right of each image. M1: primary motor cortex; mPFC: medial prefrontal cortex; PCC: posterior cingulate cortex.