Table 3.

Detailed clinical characteristics of patients with atypical language lateralization^a.

Patient number	Broca laterality index	Wernicke laterality index	Cerebellar laterality index	Handedness L = left R = right	Age at fMRI (years)	Seizure onset (years)	Seizure focus	Lesion location	Lesion type	Language (scaled scores)b
Broca Right patients
6	–0.36	0.05	0.03	R	14	0.25	Left parietal	Left parietal occipital	Cortical dysplasia	6
8	–1.00	–1.00	0.82	R	12	8	Left parietal	Normal	Unknown	Unknown
13	–0.48	–1.00	–0.01	R	15	0.003	Left parietal	Left frontal parietal; right frontal	Perinatal stroke	Unknown
25	–0.90	–1.00	1.00	L	10	8	Left frontal	Left frontal temporal	Perinatal stroke	7
37	–1.00	0.26	n/ac	R	12	7	Left frontal	Normal	Cortical dysplasia	10
38	–0.28	–0.74	0.27	L	16	1	Left frontal	Left frontal parietal occipital	Pachygyria, polymicrogyria	5
49	–0.50	1.00	1.00	R	16	7	Left temporal	Left temporal	Tumor	9
60	–0.25	–0.98	0.60	R	11	3	Left temporal	Left temporal	Polymicrogyria	4
Additional atypical patients
5	0.25	0.16	–0.48	R	14	7	Left temporal	Left temporal	Unknown	8
40	–0.10	0.17	0.42	R	10	0.003	Left temporal	Left temporal	Tumor + cortical dysplasia	7
43	0.84	0.13	–0.38	R	10	9	Left temporal	Left & right temporal	Cortical dysplasia	Unknown
51	0.22	0.89	0.98	R	14	7	Left frontal	Normal	Unknown	9
55	0.46	0.21	0.19	R	16	15	Left & right temporal	Left frontal	Vascular malformation	10

^aAtypical language defined as any patient who does not have left lateralization of Broca's and Wernicke's areas paired with right lateralization of the cerebellum.

^bLanguage function of patients with right or mixed cerebral language dominance was assessed using an average of the scaled scores obtained on the Vocabulary, Similarities, and Comprehension subtests of the Weschler Intelligence Scale for Children (WISC) or Weschler Adult Intelligence Scale (WAIS) depending on age of the child being tested.

^cNot applicable (n/a) as patient did not have above-threshold cerebellar language task activation.