Table 1.
Neuropsychological data. Normalized scores are based on an age and demographic adjusted population with a mean of 50 and a standard deviation of 10. In rows in which two scores are given, the first is performance at scan 1 (2009) and the second is performance at scan 2 (2012). In all other rows, data were only available from 2012. Indices for which the patient fell outside the confidence interval of healthy controls are highlighted. D-KEFS = Delis−Kaplan executive function system; BVMT = brief visuospatial memory test; HVLT = Hopkins verbal learning test.
| Patient score | ||
|---|---|---|
| Self-rating | Apathy | 68 |
| Disinhibition | 58 | |
| Executive dysfunction | 67 | |
| Total Score | 67 | |
| Family rating | Apathy | 110 |
| Disinhibition | 55 | |
| Executive dysfunction | 75 | |
| Total score | 85 | |
| Executive function | Animal naming | 21, 33 |
| WISC-III mazes | 48 | |
| Iowa gambling test | 41 | |
| D-KEFS word context | 47 | |
| D-KEFS tower test | 37 | |
| D-KEFS letter fluency | 33 | |
| Category fluency | 20 | |
| Category switching | 27 | |
| Memory | BVMT total immediate recall | 53, 55 |
| BVMT learning | 60, 47 | |
| BVMT delayed recall | 61, 57 | |
| HVLT learning | 33, 46 | |
| HVLT total immediate recall | 32, 29 | |
| HVLT delayed recall | 13, 18 | |
| HVLT recognition hits | −14, 17 | |
| Spatial span forward | 44, 49 | |
| Spatial span backward | 65, 45 | |
| Motor | Grip strength L hand (kg) | 40, 41 |
| Grip strength R hand (kg) | 56, 46 | |
| 9-Hole peg L (pegs/second) | 28, 21 | |
| 9-Hole peg R (pegs/second) | 63, 61 | |
| Motricity index left leg | −88, −97 | |
| Motricity index right leg | 53, 53 | |
| Combined index FIM walk + timed walk | 15, 15 | |
| Language | Word comprehension | 59, 48 |
| Commands | 53, 53 | |
| Complex ideational material | 60, 2 | |
| Boston naming test | 53, 53 | |
| Oral reading of sentences | 57, 57 | |
| Comprehension of oral reading of sentences | 53, 15 | |
| Nonword reading | 57, 57 | |
| Stem completion | 60, 60 | |
| Attention | Mesulam total misses | 59, 45 |
| Posner RT | 56, 55 | |
| Posner accuracy | 55, 55 | |
| Posner RT VF effect | 56, 57 | |
| Posner RT validity effect | 65, 67 | |
| Social cognition | Affect naming | 50 |
| Prosody comprehension | 57 | |
| Pairs comprehension | 50 | |
| Faces immediate recognition | 33 | |
| Faces delayed recognition | 43 |