Fig. 2.

Magnetic resonance imaging maps of the radial diffusivity (A–K) and the fractional isotropy (L–V) analyzed from diffusion tensor imaging scans of neonatal rat brains at 3 h (top row, A, G, L, R), 1 d (second row, B, H, M, S), 2 d (third row, C, I, N, T), 1 w (fourth row, D, J, O, U) or 4 w (fifth row, E, K, P, V) after transient hypoxia + right cerebral ischemia. Shown are representative maps of slices containing the cerebral cortex (A–E, L–P, arrows) and the posterior cerebral peduncle (G–K, R–V, arrow heads). Mean (±SD) values of ipsilateral–contralateral differences presented as a percentage of contralateral are shown in F and Q. Development of cyst is shown as off-scale measures in a dashed line bar above pericyst cortical measures. *P < 0.05; ipsilateral different from contralateral; ^†P < 0.05, cortex or pons different from cerebral peduncle within the time point; ^‡P < 0.05, different from corresponding region at 1 d; ^ψP < 0.05 different from corresponding region at 3 h, 1 d and 2 d (Two Way repeated ANOVA, Holm–Sidak multiple comparisons).